Other statins include fluvastatin, pravastatin, rosuvastatin, and simvastatin. Thank you, {{form.email}}, for signing up. However, are these fears unfounded? The first person to synthesize Lipitor was Bruce Roth, in 1985. Cholesterol experts recommend 2 grams per day. There are multiple types of statins and Lipitor is one of the more potent options. Lipitor tablets come in 10, 20, 40, and 80 milligram (mg) doses that are taken once a day, as directed by your healthcare provider. U.S. Food and Drug Administration. Study sheds light, Cholesterol deposits in the eyes: Symptoms and treatment, those with a personal or significant family history of CVD, medications that change the way the immune system works, including some. 2016;2:8. doi:10.1186/s40780-016-0040-0, What to Know About Lipitor (Atorvastatin), Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved. CNS Drugs. As with all drugs and all statins, Lipitor comes with the risk of side effects. The recommended starting dose of LIPITOR is 10 or 20 mg once daily. If you have certain medical conditions, you should not take Lipitor. CVD is the leading cause of illness and death in the United States. What are the side effects of Lipitor? In this article learn about the vegan diet, the Mediterranean diet, and the TLC diet. All content is strictly informational and should not be considered medical advice. Check your prescription and talk to your doctor to make sure you are taking the right dose for you. That's because, in addition to lowering lipids (fats), Lipitor and other statins appear to have some novel effects such as influencing immune responses, enhancing anti-inflammatory processes, and altering additional signaling pathways that aren't yet fully understood. Statin treatment in multiple sclerosis: a systematic review and meta-analysis. It is also not suitable for use while breastfeeding, as it is not clear whether the drug can enter the breast milk. The starting dose for adolescents ages 10 to 17 with an inherited form of high cholesterol is 10 mg up to a maximum dose of 20 mg once daily. You may also need to be monitored more closely if you have certain medical conditions that could be aggravated by taking the medication or increase the risk of side effects. Lipitor can cause muscle myopathy (muscle disease that causes muscle aches or weakness) and rhabdomyolysis (muscle breakdown). Effect of high-potency statins on HbA1c in patients with or without diabetes mellitus. 2015;29(4):277-91. doi:10.1007/s40263-015-0239-x, Davies JT, Delfino SF, Feinberg CE, et al. Jeffrey S. Lander, MD, is a board-certified cardiologist and the incoming President and Governor of the American College of Cardiology, New Jersey chapter. Lipitor is not suitable during pregnancy, as it can affect the development of the unborn child and may be harmful to the fetus. Jennifer Moll, MS, PharmD, is a pharmacist actively involved in educating patients about the importance of heart disease prevention. If you take too much Lipitor or overdose, seek immediate medical care. All listed dosages are according to the drug manufacturer. Changing lifelong eating habits can be scary at first, but our guide will make it easier. Good: 60 mg/dL or higher. Do not take two doses at once. According to the CDC, in 2011–2012, nearly 28 percent of adults aged 40 years and over were using some kind of prescription drug to lower cholesterol. Common side effects of Lipitor and other statins include headache, nausea, and muscle aches that often go away as your body adjusts. Statins lower cholesterol levels in the blood by blocking 3-hydroxy-3methylglutaryl coenzyme A (HMG CoA) reductase, an enzyme that's needed for the liver to produce cholesterol. Patients should take care if they are also using: Some interactions could lead to a condition known as rhabdomyolysis, a muscle wasting disease. Put Down the Grapefruit Juice, Atorvastatin treatment and LDL cholesterol target attainment in patients at very high cardiovascular risk, Statin treatment in multiple sclerosis: a systematic review and meta-analysis, Current and emerging uses of statins in clinical therapeutics: a review, Highlights of prescribing information: Lipitor, Statin-induced rhabdomyolysis: a comprehensive review of case reports, Effect of high-potency statins on HbA1c in patients with or without diabetes mellitus, Low-density lipoprotein (LDL, considered "bad" cholesterol), Apolipoprotein B (apo B, a protein involved in the metabolism of lipids that is also part of lipoproteins, such as LDL), Swollen/sore nasal passages and the back of your throat (nasopharyngitis), Unexplained muscle aches, weakness, or soreness, Severe metabolic, endocrine, and electrolyte disorders. Patients who use Lipitor should not consume more than 1–2 small glasses of grapefruit juice in a day, because this can affect how the drug works. A urine test may reveal a raised white blood cell count. Current and emerging uses of statins in clinical therapeutics: a review. People also know it as atorvastatin. It reduces levels of triglycerides and “bad” LDL cholesterol in the blood and increases levels of “good” HDL cholesterol. Lipitor is effective at lowering cholesterol; however, its use may be limited by side … 2014;66(2):124–132. This question has received a great deal of attention. Lipid Insights. Some can be serious or require treatment, so it's important to be aware of them. Cholesterol can deposit around the eyes and form fatty, yellow lumps. The Centers for Disease Control and Prevention (CDC), estimate that having high cholesterol doubles the risk of heart disease. Lipitor is its brand name. Store the tablets at a controlled room temperature that's ideally 68 to 77 degrees F. If you miss a dose of Lipitor, take it as soon as you remember. Statins like Lipitor are sometimes prescribed off-label to try to stop the progression of autoimmune or chronic inflammatory diseases, such as secondary progressive multiple sclerosis (SPMS).. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Never increase your dose without your doctor's OK. Each type of statin has unique interactions with other medications and risks of side effects, so your doctor will take into account what other medications you're on, how elevated your cholesterol levels are, and what other conditions you have when determining which statin to prescribe., Other types of statin tablets include Mevacor (lovastatin), Pravachol (pravastatin), Crestor (rosuvastatin), Zocar (simvastatin), and Livalo (pitavastatin). ... the average LDL had fallen to 77 mg/dL compared with 101 mg/dl in the low-dose Lipitor … These can happen when cholesterol accumulates in the blood vessels. Your dosage of Lipitor may need to be lowered or stopped. Read our, Medically reviewed by Richard N. Fogoros, MD, Medically reviewed by Yasmine S. Ali, MD, MSCI, Verywell Health uses cookies to provide you with a great user experience. Borderline: 130 to 159 mg/dL. Looking to start a diet to better manage your cholesterol? Statins reduce the levels of bad cholesterol, and this helps to prevent coronary artery disease and serious complications of CVD, such as angina, stroke, and heart attack. Lipitor is an adjunct therapy to diet and is typically prescribed in cases where lifestyle changes (diet, physical activity) or other medications are not effective in lowering cholesterol. If it does, it could harm the infant. Patients with HIV or a bacterial infection, such as tuberculosis (TB), may also benefit from the potential effects of these drugs on the immune system. Cholesterol and triglycerides can clog blood vessels and increase heart disease risks. Thapar M, Russo MW, Bonkovsky HL. Physiother Can. If you have a history of heart attacks or you're at a very high risk of a heart attack or stroke, you may need to aim even lower (below 70 mg/dL, or 1.8 mmol/L). Statins are also sometimes used off-label for neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease, since high cholesterol levels are associated with disease progression. The enzyme is vital for cholesterol production. If a person has dyslipidemia, or hyperlipidemia, they have a high level of cholesterol, triglycerides, or both, in the blood. doi:10.3138/ptc.2012-65. Lowers cholesterol: Lipitor (atorvastatin) is an excellent drug for lowering cholesterol. MNT is the registered trade mark of Healthline Media. This was an increase of nearly 8 percent since 2003. Symptoms of rhabdomyolysis include muscle soreness/weakness and dark urine. The standard starting dose for adults is 10 to 20 mg. Those who require at least a 45% reduction in LDL cholesterol may be begin with a 40-mg dose. In these cases, your healthcare provider may place you on a different treatment to lower your lipids: Talk to your doctor about all medications, supplements, and vitamins that you currently take. Some people have abnormally high levels of lipids in their blood. The name of this is dyslipidemia, or hyperlipidemia. J Pharm Health Care Sci. Your physician may slowly increase the dose as needed based upon your LDL levels and your response to the medication. Low: 39 mg/dL or lower. CVD includes coronary heart disease, stroke, or peripheral vascular disease. By using Verywell Health, you accept our, Cholesterol & Triglycerides: What You Need to Know, An Overview of Drug-Induced Liver Disease, How Zocor (Simvastatin) Works to Lower Your Cholesterol, An Ace Inhibitor Used for Hypertension and Heart Failure, General Information About Livalo (Pitavastatin), Crestor: Uses, Side Effects, Dosages, Interactions, Metoprolol: Used to Treat High Blood Pressure and Angina, What to Know Before Starting a Bile Acid Resin to Lower LDL, How the Atrogin-1 Gene May Cause Muscle Pain for Statin Users, Taking Statins? Lipitor (atorvastatin) is a cholesterol-lowering medication that belongs to the statin class of drugs. You may need blood tests to check your liver. If you experience any signs of allergic reaction, seek urgent medical attention. Do not drink grapefruit juice while taking this medication since it can impair your body's ability to metabolize the drug and increase blood concentrations of Lipitor., Drugs and supplements can also interact with Lipitor, and some can increase the likelihood of experiencing side effects, especially myopathy. Low-density lipoprotein (LDL) cholesterol. Simvastatin and pravastatin were more well-tolerated in the study, yet not as potent or effective at lowering cholesterol as atorvastatin or rosuvastatin. Fluvastatin and lovastatin are additional low-potency options. The latest study concludes that the answer is…. While you are taking Lipitor, your doctor will have you come in periodically for blood tests to monitor your cholesterol levels and to check if your dosage needs to be adjusted. These changes include; not smoking, eating a healthy diet, sitting less and exercising more, and maintaining a healthy waistline of less than 40 inches for men and less than 35 inches for women. If you are experiencing any side effects from taking Lipitor that become prolonged or bothersome, you should let your healthcare provider know. © 2004-2020 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Clin Res Cardiol. Your risk of experiencing rhabdomyolysis can increase if you are taking other medications or are older than 65.. It is quickly absorbed, reaching its peak concentration in the blood within about two hours. Lipitor starts to lower cholesterol within about two weeks of starting the medication. LIPITOR can be administered as a single dose at any time of the day, with or without food. Research has found that rosuvastatin reduces LDL cholesterol by an average of 51% followed by atorvastatin at 45%, simvastatin at 37%, and pravastatin at 25%.. All rights reserved. As well as using Lipitor, people should follow a low-fat, low-cholesterol, healthful diet. Some people experience allergic reactions to atorvastatin. Statins and liver injury. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional, Eating dried fruit linked to better overall diet and health, Loneliness and hunger share a home in the brain, Tuberculosis vaccine may help protect against COVID-19, Jaw-clenching and teeth-grinding during the pandemic, The impact of historical trauma on American Indian health equity. P, Robles PG, Mathur S. Statin-induced rhabdomyolysis: a review a heart attack and increase heart disease.. Tell your healthcare provider if you have certain medical conditions, you should not take Lipitor class drugs. Lipid levels with a high risk of heart disease cholesterol deposits here the body from producing bad cholesterol by an... Centers for disease Control and prevention ( CDC ), estimate that having high cholesterol the., et al or require treatment, so it 's important to be lowered or.. 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